[HTML][HTML] Injectable thermoresponsive hydrogels as drug delivery system for the treatment of central nervous system disorders: A review

E Bellotti, AL Schilling, SR Little, P Decuzzi - Journal of controlled release, 2021 - Elsevier
… viscous hydrogel forms a depot for the sustained release of … the treatment and management
of brain tumors, spinal cord and … containing neurotrophin 3 (NT-3) loaded microspheres on …

[HTML][HTML] Biocompatible copolymer formulations to treat glioblastoma multiforme

LCS Erthal, OL Gobbo, E Ruiz-Hernandez - Acta biomaterialia, 2021 - Elsevier
… PLGA (Poly Lactic-co-Glycolic Acid) PLGA nanofiber discs … covalently linked to two
camptothecin drug molecules, which … of having a sustained release of drugs, for example through

[HTML][HTML] Local delivery and glioblastoma: why not combining sustained release and targeting?

C Gazaille, M Sicot, P Saulnier, J Eyer… - Frontiers in Medical …, 2021 - frontiersin.org
… with BCNU is developed as microspheres, compressed into 1.4 cm … the hydrogel without
camptothecin (median survival of 36 days). … Zhao et al. have studied poly (lactic-co-glycolic acid) …

[PDF][PDF] SMART HYDROGEL-BASED INJECTABLE SYSTEMS FOR BREAST CANCER THERANOSTICS

HNC CARRÊLO - 2023 - run.unl.pt
Microspheres consist of a porous matrix that has the cargo … sustained release profile;
release of the decrease treatment efficiency and the patient's quality of life, especially when using

PEGylated polylactide (PLA) and poly (lactic-co-glycolic acid)(PLGA) copolymers for the design of drug delivery systems

DR Perinelli, M Cespi, G Bonacucina… - Journal of …, 2019 - Springer
… demonstrated that mPEG–camptothecin reduced the Tgel … drug delivery such as microspheres,
nanoparticles, and liposomes. … co-polymer to achieve sustained release. Chemokines are …

PLGA-based biodegradable microspheres in drug delivery: recent advances in research and application

Y Su, B Zhang, R Sun, W Liu, Q Zhu, X Zhang… - Drug …, 2021 - Taylor & Francis
Poly (lactic-co-glycolic acid) copolymer (PLGA) is one of the … consisting of anti-cancer drug
camptothecin (CPT) were … -19 cells due to their sustained release ability. In conclusion, PLGA …

Polymeric and lipid-based drug delivery systems for treatment of glioblastoma multiforme

R Duwa, F Emami, S Lee, JH Jeong, S Yook - Journal of Industrial and …, 2019 - Elsevier
… a thermo-reversible gel loaded with polymeric microspheres … ] designed camptothecin (CPT)-loaded
PLGA microspheres … of sustained release microspheres into tumor perimeters was …

[HTML][HTML] Design of biopolymer-based interstitial therapies for the treatment of glioblastoma

ES Pena, EG Graham-Gurysh, EM Bachelder… - International journal of …, 2021 - mdpi.com
… With sustained release of a drug locally, therapeutic … (PGA), and their copolymer form
poly(lactic-co-glycolic) acid (PLGA), … hydrogels without PLGA microspheres or PTX-loaded PLGA …

Engineered hydrogels for brain tumor culture and therapy

J Thakor, S Ahadian, A Niakan, E Banton… - Bio-design and …, 2020 - Springer
sustained release manner for efficient glioma chemotherapy. For this purpose, poly(lactic-co-glycolic
acid… beneficial for drug treatments as they can provide sustained release of different …

Long-acting therapeutic delivery systems for the treatment of gliomas

S Padmakumar, MM Amiji - Advanced Drug Delivery Reviews, 2023 - Elsevier
Cancer sticky hydrogel … Pediatric brain tumors are also one of the leading causes of pediatric
malignancies [11]. Pilocytic astrocytoma, considered to be the most common brain tumor in …